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Through the President’s Emergency Plan for AIDS (acquired immunodeficiency syndrome) Relief (PEPFAR) Country Operational Plan 2023 (COP23), the United States Government (USG) will support the Government of Ukraine’s (GOU’s) work, in close partnership with civil society and other stakeholders, toward our shared goal of ending Human immunodeficiency virus (HIV) as a public health threat by 2030, despite the horrors of Russia’s full-scale war against Ukraine. In COP23, PEPFAR Ukraine will provide unprecedented support paired with maximum flexibility to ensure Ukrainian public health actors are able to protect what had been a decade of steady progress toward 95-95-95 through wartime disruptions and onward to victory and recovery.