Online Pharmacy PrEP and PEP: Technical considerations and learnings from Kenya

26 July 2024

This document, developed by PATH, is intended as a how-to implementation guide for providing oral pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) via online pharmacy service delivery (ePrEP/ePEP) based on learnings and evidence from the ePrEP Kenya pilot study that ran from October 2022 through July 2024.

The guide was developed to support ministries of health and their partners as they develop strategies for HIV prevention services— specifically, ePrEP and ePEP delivery through a telehealth and online pharmacy model. It outlines a suggested approach that can be tailored based on epidemiological, social, economic, health systems, and policy contexts. Service delivery partners should exercise flexibility and adapt these recommendations and tools to their specific contexts, available resources, and infrastructure.

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Global Acute HIV Infection Algorithm Job Aids for Providers

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Daily Oral PrEP, PrEP Ring, and CAB PrEP Template Guidelines (Spanish)

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2024 Q3 Global PrEP Tracker

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Oral PrEP, PrEP Ring, and CAB PrEP Template Guidelines (English)

External Link

Pre-Exposure Prophylaxis Implementation Gaps among People Vulnerable to HIV Acquisition: A cross-sectional analysis in two communities in western Kenya, 2021–2023

This article, from Journal of the International AIDS Society, examines PrEP awareness, uptake, and persistence among participants enrolling into an HIV incidence cohort in Kenya.

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Initiation and Continued Use of Oral Pre-Exposure Prophylaxis among Pregnant and Postpartum Women in South Africa (PrEP-PP): A demonstration cohort study

This article from The Lancet HIV describes the results of a demonstration study in South Africa, PrEP-PP, to integrate oral PrEP provision into public clinics offering antenatal and postnatal care to pregnant and lactating people.

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Acceptability of Six-Monthly PrEP Dispensing Supported with Interim HIV Self-Testing to Simplify PrEP Delivery in Kenya: Findings from qualitative research

This article from BMC Health Services Research discusses the results of a pilot in Kenya to explore the acceptability of dispensing PrEP twice a year, with interim HIV self-testing, versus quarterly, with clinic-based HIV testing.

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Dynamic Choice HIV Prevention with Cabotegravir Long-acting Injectable in Rural Uganda and Kenya: A randomised trial extension

This article from The Lancet HIV discusses the results of the SEARCH dynamic choice study conducted in Kenya and Uganda, comparing outcomes between one group offered a choice between oral PrEP, post-exposure prophylaxis, and cabotegravir for PrEP, and a second group receiving the standard of care.

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Adolescent Girls and Young Women Overcoming Adherence Challenges with Vaginal and Oral PrEP Use: A longitudinal qualitative study from a crossover trial in South Africa, Uganda, and Zimbabwe

This article from AIDS and Behavior explores South African, Ugandan, and Zimbabwean adolescent girls and young women’s experiences in a crossover trial of two HIV prevention products: daily oral PrEP and a monthly dapivirine vaginal ring.