Resource Library

Developing and Introducing a Dual Prevention Pill- Oral PrEP & oral contraception for HIV and pregnancy prevention

A coalition of partners is developing a novel Dual Prevention Pill (DPP) for prevention of pregnancy and HIV acquisition in high-need countries. In East and Southern Africa — where the DPP is initially planned for introduction — 65 percent of new HIV infections are amongst women aged 15 and over, and 16 percent of women…

Community/Advocacy, Research

CHARISMA Mobile: Developing a digital resource for empowerment counseling, community health clinic model for agency in relationships and safer microbicide adherence

CHARISMA is a PEPFAR- and USAID-funded empowerment counseling intervention designed to help women use oral pre-exposure prophylaxis and other antiretroviral-based HIV prevention technologies safely and effectively by addressing dynamics of their relationships with male partners, including exposure to intimate partner violence. The intervention, designed to be delivered by lay counselors, is being adapted into a…

Research, Service Delivery

PrEP-it

Stakeholders at the forefront of oral PrEP delivery have encountered several programmatic challenges such as difficulty in setting targets, tracking the continuum of PrEP delivery, and estimating program costs and impact. In response, PEPFA) has developed a Microsoft Excel-based tool called PrEP-it for oral PrEP implementation planning, monitoring and evaluation.

Financing & Costing, Monitoring & Evaluation, Research, Service Delivery, Supply Chain Management

Stakeholder Conversations to Inform Delivery of New HIV Prevention Methods in South Africa

Little is known about what is needed for health care providers to ensure adequate counseling on method choice, referral mechanisms, and supportive follow-up with regards to multiple biomedical HIV prevention methods. The goal of these conversations with stakeholders in South Africa was to gain input on implementation considerations from provider and potential end-user perspectives, as…

Oral PrEP Training for Providers (French)

This modifiable training slide deck was developed with support from USAID and PEPFAR through the Meeting Targets and Maintaining Epidemic Control (EpiC) project. The materials reflect WHO guidance as of 4 April 2022 and build on lessons learned from nearly ten years of oral PrEP implementation. The training is built so that it can be…

Service Delivery

Stakeholder conversations to inform delivery of new HIV prevention methods in Zimbabwe

Little is known about what is needed for health care providers to ensure adequate counseling on method choice, referral mechanisms, and supportive follow-up with regards to multiple biomedical HIV prevention methods. The goal of these conversations with stakeholders in Zimbabwe was to gain input on implementation considerations from provider and potential end-user perspectives, as well…

Eswatini Dapivirine Ring Consultation Analysis

This PrEP ring consultation analysis can support introduction of the dapivirine vaginal ring in Eswatini and is based on several inputs, including secondary research and interviews with key stakeholders in Eswatini.

Frequently Asked Questions about the Dual Prevention Pill

The Dual Prevention Pill (DPP) is a single, co-formulated, daily oral pill containing oral pre-exposure prophylaxis (PrEP) and combined oral contraception (COC) that prevents both HIV and pregnancy. The DPP will add to the contraceptive and HIV prevention toolbox and will be the first multi-purpose prevention technology (MPT) to go to market since male and…

Service Delivery

Guidelines for PrEP Ring Pilot Implementation Studies

The intent of this document is to provide adaptable guidelines for the design of Dapivirine ring pilot implementation or post-introduction operations studies to help shape national ring guidelines.

Research, Service Delivery

Modelling Impact of Injectable Cabotegravir for PrEP on Drug Resistance

An important consideration in the scale-up of injectable cabotegravir (CAB) for PrEP is the potential for development of Integrase Strand Transfer Inhibitor (INSTI) resistance. To help stakeholders understand this issue further, Professor Andrew Phillips from University College London shared the results of an exercise modelling the impact of the introduction of CAB for PrEP on…

Financing & Costing, Testing