Resource Library

Results of open-label study of a vaginal ring for HIV prevention suggest women are interested in and willing to use it

This article from the Microbicide Trials Network shares the results of an open-label study of a vaginal ring for HIV prevention

Community/Advocacy, Demand Creation/Marketing, Research

Adherence to the Dapivirine vaginal ring and oral PrEP among adolescent girls and young women in Africa: interim results from the REACH study

Adolescent girls and young women (AGYW) account for most new HIV infections in sub-Saharan Africa. WHO has endorsed oral PrEP and dapivirine vaginal ring (ring) for women at substantial risk of HIV infection. However, adherence to both products was lower among younger women in randomized placebo-controlled trials. The authors of this article assessed interim safety,…

Research

Microbicide Trials Network-042 – DELIVER Study

Microbicide Trials Network-042/DELIVER is a Phase IIIb open-label study designed to evaluate the safety and acceptability of the monthly dapivirine vaginal ring and oral PrEP in pregnant women.

Research

PEPFAR Panorama Spotlight

PEPFAR's Panorama Spotlight tracks program results achieved through PEPFAR support

Monitoring & Evaluation

Health system adaptations and considerations to facilitate optimal oral pre-exposure prophylaxis scale-up in sub-Saharan Africa

Countries in sub-Saharan Africa have progressively scaled up oral PrEP as part of combination HIV prevention. Initial scale-up efforts have generated progress, drawing lessons from existing HIV interventions, such as antiretroviral therapy and biomedical prevention. However, beset by unprepared health systems, scale-up has been slow. This review synthesises literature on essential considerations for PrEP scale-up,…

Normative Guidance/Policies, Research, Service Delivery

Barriers to Provision HIV Biomedical Prevention Services in sub-Saharan Africa

AVAC conducted a desk review of the HIV prevention policy landscape in eight countries in sub-Saharan Africa. This analysis includes: training requirements for provision of PrEP and contraceptives; clinical guidelines; National Strategic Plans for HIV and Sexual and Reproductive Health; implementation strategies; national policies on age of consent and the criminality of same-sex relationships; in-depth…

Normative Guidance/Policies, Research

Developing and Introducing a Dual Prevention Pill- Oral PrEP & oral contraception for HIV and pregnancy prevention

A coalition of partners is developing a novel Dual Prevention Pill (DPP) for prevention of pregnancy and HIV acquisition in high-need countries. In East and Southern Africa — where the DPP is initially planned for introduction — 65 percent of new HIV infections are amongst women aged 15 and over, and 16 percent of women…

Community/Advocacy, Research

CHARISMA Mobile: Developing a digital resource for empowerment counseling, community health clinic model for agency in relationships and safer microbicide adherence

CHARISMA is a PEPFAR- and USAID-funded empowerment counseling intervention designed to help women use oral pre-exposure prophylaxis and other antiretroviral-based HIV prevention technologies safely and effectively by addressing dynamics of their relationships with male partners, including exposure to intimate partner violence. The intervention, designed to be delivered by lay counselors, is being adapted into a…

Research, Service Delivery

1 March 2022

Stakeholder conversations to inform delivery of multiple HIV prevention methods in Kenya

This report highlights findings from stakeholder conversations implemented in Kenya as part of the PROMISE Collaboration to gain input on implementation considerations for the introduction of the PrEP ring alongside oral PrEP and future inclusion of additional prevention methods for women

Research, Service Delivery

1 March 2022

AGYW from Kenya and South Africa: The POWER demonstration project

This poster outlines results from the POWER demonstration project, including characterizing young women who initiate PrEP in Kenya and South Africa, determining PrEP persistence and patterns of use, assessing HIV incidence and drug resistance among PrEP seroconverters, and evaluating different PrEP delivery models.

Research, Service Delivery