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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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21 December 2022

Feasibility and Preliminary Effectiveness of Integrating HIV Prevention into an Adolescent Empowerment and Livelihood Intervention at Youth Clubs in Rural Uganda

This article from AIDS Care examines the feasibility and preliminary effectiveness of integrating HIV prevention into youth clubs implementing an “empowerment and livelihood for adolescents” intervention in rural Uganda.

Research, Service Delivery

External Link
21 December 2022

Adherence Challenges with Daily Oral Pre-exposure Prophylaxis during Pregnancy and the Postpartum Period in South African Women: A cohort study

This article from the Journal of the International AIDS Society explores pharmacologic measures of PrEP adherence during pregnancy and postpartum and the factors related to optimal adherence during periods of sexual activity in this population.

Research

External Link
21 December 2022

End-user Research in Support of Long-acting Systemic Antiretroviral Delivery Systems: Insights from qualitative research with providers and target users in South Africa

This article from BMC Infectious Diseases describes qualitative research investigating perceptions of and preferences for a long-acting, biodegradable implantable PrEP product designed to address challenges relating to adhering to a daily pill regimen amongst adolescent girls and young women and sex workers in Guateng Province, South Africa.

Research

External Link
5 December 2022

Zambia Activation Session for Youth-focused HIV Prevention Programming

In collaboration with the Ministry of Health and National AIDS Council of the Government of the Republic of Zambia, MOSAIC convened the country’s first Activation Session for Youth-focused HIV Prevention Programming in Lusaka in July 2022. The session focused on challenges and potential solutions for interventions engaging adolescent girls and young women and their parents…

Demand Creation/Marketing, Service Delivery

Document
5 December 2022

Characterizing the Impact of the COVID-19 Pandemic on HIV PrEP care: A review and synthesis of the literature

This review from the journal AIDS and Behavior provides an examination of the influences of the COVID-19 pandemic on engagement in the PrEP care continuum, and looks at the barriers and facilitators to PrEP uptake during this time.

Research, Service Delivery

External Link
5 December 2022

PrEP Among Pregnant and Lactating People in 18 PEPFAR-Supported Countries: A review of HIV strategies and guidelines

This article from Global Health: Science and Practice examines the evolution of strategies and guidance on PrEP services for pregnant and lactating people from 18 countries supported by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR).

Normative Guidance/Policies, Research

External Link
2 December 2022

Building Community Acceptance for PrEP Use among Adolescent Girls and Young Women in Sub-Saharan Africa

MOSAIC held an Action Tank in 2022 which sought to determine which community influencers impact PrEP use among adolescent girls and young women (AGYW) and the behavioral determinants that influence their support of AGYW PrEP use, as well as to identify promising community acceptance interventions that directly address these determinants for adaptation and evaluation under…

Community/Advocacy, Demand Creation/Marketing

Document
18 November 2022

Uptake of and Adherence to Oral Pre-exposure Prophylaxis among Adolescent Girls and Young Women at High Risk of HIV-Infection in Kampala, Uganda: A qualitative study of experiences, facilitators and barriers

This article from BMC Women’s Health describes the results of a qualitative study exploring the experiences, facilitators and barriers of PrEP uptake and adherence to PrEP among adolescent girls and young women in Kampala, Uganda.

Research, Service Delivery

External Link
18 November 2022

Self-reported and Pill Count Measures of Adherence to Oral HIV PrEP among Female Sex Workers Living in South-Western Uganda

This article from PLOS One reports on a study evaluating PrEP adherence amongst female sex workers in southwestern Uganda using clinic-based pill counts and self-reported measures, and examines factors associated with protective levels of adherence.

Research, Service Delivery

External Link
18 November 2022

Transgender Women in HPTN 083: An evaluation of safety, efficacy, and gender affirming hormonal therapy interactions with long-acting cabotegravir

This poster from AIDS 2022 presents an analysis of results from the HPTN 083 study, looking at the impact of feminizing gender affirming hormones on cabotegravir (CAB) for PrEP pharmacokinetics.

Research

Document