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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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10 February 2023

Coordinating Implementation Science for CAB for PrEP: Focus on Research and Surveillance during Pregnancy and Breastfeeding

These notes outline the key takeaways of a Think Tank focussing on CAB for PrEP implementation research and surveillance during pregnancy and breastfeeding. The Think Tank was part of an ongoing series by BioPIC and the WHO on coordinating implementation science for injectable CAB for PrEP.

Monitoring & Evaluation, Research

Document
10 February 2023

PrEPVacc Study

The PrEPVacc trial, taking place in Mozambique, South Africa, Tanzania, and Uganda from 2018 to 2024, combines an evaluation of experimental HIV vaccines and oral PrEP at the same time. The PrEP arm of the trial compares the effectiveness of TDF/FTC (Truvada) with F/TAF (Descovy).

Research

External Link
6 February 2023

Optimizing Uptake of Long-Acting Injectable Pre-exposure Prophylaxis for HIV Prevention for Men Who Have Sex with Men

This article from AIDS and Behavior describes the results of a discrete choice experiment on preferences for oral or injectable PrEP amongst gay, bisexual, and other men who have sex with men in the USA, including mode of administration, side-effects, monetary cost, and time cost.

Research

External Link
6 February 2023

Pregnancy and Neonatal Safety Outcomes of Timing of Initiation of Daily Oral Tenofovir Disoproxil Fumarate and Emtricitabine Pre-exposure Prophylaxis for HIV Prevention (CAP016): An open-label, randomised, non-inferiority trial

This article from The Lancet HIV describes the results of a trial to compare pregnancy and neonatal outcomes in women exposed and not exposed to oral PrEP (TDF/FTC) during pregnancy in Durban, South Africa.

Research

External Link
1 February 2023

Discontinuation of Government Subsidized HIV Pre-exposure Prophylaxis in Australia: A whole-of-population analysis of dispensing records

This article from the Journal of the International AIDS Society examines the impact of discontinuation on overall PrEP usage, the proportion of PrEP users who discontinue and the predictors of discontinuation in Australia.

Monitoring & Evaluation, Research

External Link
23 January 2023

Cost-effectiveness Analysis of the Daily HIV Pre-exposure Prophylaxis in Men who Have Sex with Men in Barcelona

This article from PLOS One models the cost-effectiveness of daily oral PrEP use amongst gay and bisexual men who have sex with men in Barcelona, Spain.

Financing & Costing, Research

External Link
23 January 2023

Estimating the Impact of HIV PrEP Regimens Containing Long-acting Injectable Cabotegravir or Daily Oral Tenofovir Disoproxil Fumarate/Emtricitabine among Men who Have Sex with Men in the United States: A mathematical modelling study for HPTN 083

This article from The Lancet Regional Health- Americas describes the results of a modelling exercise which compares the potential population-level impact of oral PrEP (TDF/FTC) and Cabotegravir for PrEP among gay and bisexual men who have sex with men in Atlanta, Georgia, USA.

Research

External Link
23 January 2023

Nurse-facilitated PrEP Delivery for Adolescent Girls and Young Women Seeking Contraception at Retail Pharmacies in Kisumu, Kenya

This article from AIDS evaluates PrEP uptake, initiation, and continuation within a nurse-facilitated pharmacy-based delivery model for Kenyan adolescent girls and young women seeking contraception at retail pharmacies.

Research, Service Delivery

External Link
23 January 2023

Efficacy of Daily Text Messaging to Support Adherence to HIV Pre-Exposure Prophylaxis (PrEP) among Stimulant-Using Men Who Have Sex with Men

This article from Substance Use & Misuse evaluates the efficacy of the individualized Texting for Adherence Building (iTAB) intervention for PrEP adherence among 119 gay and bisexual men who have sex with men who use stimulants in California, USA.

Research, Service Delivery

External Link
18 January 2023

HIV Implementation Literature Review Dashboard

The Literature Review Dashboard, developed by Northwestern University’s HIV Implementation Science Coordination Initiative, is an interactive database tool comprised of hundreds of U.S. studies that identify multilevel determinants of HIV implementation. The aim of this tool is to give implementation researchers and practitioners access to the articles and implementation findings of systematic reviews that can…

Research, Service Delivery

External Link