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Resource Library

The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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16 July 2024

Pre-Exposure Prophylaxis and Adolescent Girls and Young Women in Eastern and Southern Africa: The latest insights

Eastern and southern Africa (ESA) is the world’s most heavily HIV-impacted region, with adolescent girls and young women (AGYW) disproportionately affected. To support the scale-up of PrEP amongst AGYW in ESA, in September 2021 UNICEF and partners released the implementation brief “Improving the Quality of Pre-Exposure Prophylaxis Implementation for Adolescent Girls and Young Women in…

Research, Service Delivery

Document
15 July 2024

Strengthening and Harmonising PrEP Indicators

Experience gained from the implementation and analysis of PrEP programs reveals significant limitations in current indicators for global PrEP monitoring. Metrics focused on numbers of ‘people receiving PrEP’ struggle to track individual clients, overlook method switching and discontinuous patterns of PrEP use, and present challenges in using indicator data to estimate PrEP coverage and program…

Monitoring & Evaluation

Presentation
8 July 2024

The Lens on LEN

In late June 2024, Gilead Sciences announced an early review of the data of the PURPOSE 1 trial by an independent monitoring board, which found that injectable lenacapavir (LEN) provided as prevention was safe and highly effective against HIV. The product is being tested among 5,300 HIV-negative cisgender women ages 16-25 in Uganda and South…

Research

Document
20 June 2024

Establishing and Implementing a Youth Network for HIV Prevention: A case study of meaningful youth engagement in Zimbabwe

This case study, developed by the South-South Learning Network, Global HIV Prevention Coalition, and Insight 2 Implementation, shares four key learnings from Zimbabwe’s experience of setting-up a successful youth network to meaningfully engage young people in designing, developing, delivering and monitoring the HIV prevention response for adolescents and young people. In addition to the English…

Community/Advocacy

Document
18 June 2024

Zimbabwe Strategic Direction Summary, 2023

The US President’s Emergency Plan for AIDS Relief (PEPFAR) Zimbabwe interagency team collaborated with key partners including the Government of Zimbabwe (GoZ), the Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), civil society organizations (CSOs), and other bilateral and multilateral health development partners to develop the 2023 Country Operational Plan (COP23) for FY 2024/25.…

Normative Guidance/Policies

Document
18 June 2024

Vietnam Strategic Direction Summary, 2023

Standing at the 20th anniversary of the President’s Emergency Plan for AIDS Relief (PEPFAR), Vietnam can claim many successes achieved throughout this history. As the first Asian country to receive PEPFAR support and currently the only Asian country with a standalone bilateral COP, Vietnam holds a unique place in PEPFAR’s progress and milestones over the…

Normative Guidance/Policies

Document
18 June 2024

Ukraine Strategic Direction Summary, 2023

Through the President’s Emergency Plan for AIDS (acquired immunodeficiency syndrome) Relief (PEPFAR) Country Operational Plan 2023 (COP23), the United States Government (USG) will support the Government of Ukraine’s (GOU’s) work, in close partnership with civil society and other stakeholders, toward our shared goal of ending Human immunodeficiency virus (HIV) as a public health threat by…

Normative Guidance/Policies

Document
18 June 2024

Uganda Strategic Direction Summary, 2023

Uganda continues to accelerate reductions in new HIV infections and AIDS-related deaths, despite chronic infectious disease outbreaks, health system stressors, and economic fragility. This is reflected in Uganda’s HIV clinical cascade, which demonstrates substantial progress in finding, diagnosing, and successfully treating people living with HIV (PLHIV) since 2016. Today, an estimated 92% of Ugandans living…

Normative Guidance/Policies

Document
18 June 2024

Tanzania Strategic Direction Summary, 2023

PEPFAR/Tanzania (PEPFAR/T) has an unprecedented and unique opportunity to utilize multiple updated national data sources to formulate a robust Country Operational Plan 2023 (COP23). COP23 planning was informed by preliminary unweighted key results from the Tanzania HIV Impact Survey (THIS) 2022-2023, Bio-Behavioral Survey 2022 (BBS 2022), 2022 Tanzania Demographic Health Survey, Malaria Indicator Survey (2022…

Normative Guidance/Policies

Document
18 June 2024

South Sudan Strategic Direction Summary, 2023

South Sudan is a country in a protracted crisis. It has been plagued by conflict, flooding, corruption, poor governance, economic mismanagement, and increasing dependency on donor assistance since its independence in 2011. The United States has been a strong supporter of South Sudan, providing over $6.6 billion in humanitarian aid and development assistance since 2011…

Normative Guidance/Policies

Document