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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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27 February 2023

Risk-based versus Universal PrEP Delivery during Pregnancy: A cluster randomized trial in Western Kenya from 2018 to 2019

This article from the Journal of the International AIDS Society reviews the results of the PrEP Implementation for Mothers in Antenatal Care (PrIMA) study, which compared two models of PrEP delivery to pregnant populations in western Kenya.

Research, Service Delivery

External Link
20 February 2023

High PrEP Uptake and Objective Longitudinal Adherence among HIV-exposed Women with Personal or Partner Plans for Pregnancy in Rural Uganda: A cohort study

This article from PLOS Medicine describes the impact of the Healthy Families-PrEP intervention to support PrEP use as part of HIV prevention during periconception and pregnancy periods in Uganda.

Research, Service Delivery

External Link
10 February 2023

Coordinating Implementation Science for CAB for PrEP: Focus on Research and Surveillance during Pregnancy and Breastfeeding

These notes outline the key takeaways of a Think Tank focussing on CAB for PrEP implementation research and surveillance during pregnancy and breastfeeding. The Think Tank was part of an ongoing series by BioPIC and the WHO on coordinating implementation science for injectable CAB for PrEP.

Monitoring & Evaluation, Research

Document
6 February 2023

Pregnancy and Neonatal Safety Outcomes of Timing of Initiation of Daily Oral Tenofovir Disoproxil Fumarate and Emtricitabine Pre-exposure Prophylaxis for HIV Prevention (CAP016): An open-label, randomised, non-inferiority trial

This article from The Lancet HIV describes the results of a trial to compare pregnancy and neonatal outcomes in women exposed and not exposed to oral PrEP (TDF/FTC) during pregnancy in Durban, South Africa.

Research

External Link
17 January 2023

HIV Prevention Ambassador Training Package and Toolkit

The HIV Prevention Ambassador Training Package and Toolkit is designed for community-based organizations and other groups to train HIV Prevention Ambassadors with the goal of promoting the meaningful engagement of communities and potential and current PrEP users in the rollout of oral PrEP for HIV prevention.

Community/Advocacy, Demand Creation/Marketing

Document
3 January 2023

Southern African HIV Clinicians Society PrEP Training Curriculum

This training curriculum was developed by the Southern African HIV Clinicians Society to support implementers rolling out PrEP. Module 1a: A basic overview and introduction to PrEP Module 1b: Evidence of PrEP effectiveness Module 2: Providing PrEP- the basics Module 3a: Overview of key populations Module 3b: Gay and bisexual men who have sex with…

Demand Creation/Marketing, Research, Service Delivery

21 December 2022

Adherence Challenges with Daily Oral Pre-exposure Prophylaxis during Pregnancy and the Postpartum Period in South African Women: A cohort study

This article from the Journal of the International AIDS Society explores pharmacologic measures of PrEP adherence during pregnancy and postpartum and the factors related to optimal adherence during periods of sexual activity in this population.

Research

External Link
5 December 2022

Characterizing the Impact of the COVID-19 Pandemic on HIV PrEP care: A review and synthesis of the literature

This review from the journal AIDS and Behavior provides an examination of the influences of the COVID-19 pandemic on engagement in the PrEP care continuum, and looks at the barriers and facilitators to PrEP uptake during this time.

Research, Service Delivery

External Link
5 December 2022

PrEP Among Pregnant and Lactating People in 18 PEPFAR-Supported Countries: A review of HIV strategies and guidelines

This article from Global Health: Science and Practice examines the evolution of strategies and guidance on PrEP services for pregnant and lactating people from 18 countries supported by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR).

Normative Guidance/Policies, Research

External Link
30 November 2022

Approaches to Accelerating the Study of New Antiretrovirals in Pregnancy

This article from the Journal of the International AIDS Society proposes principles and a framework to enhance and accelerate the study of new antiretrovirals in pregnancy, both for treatment and prevention.

Research

External Link