Resource Library

Dapivirine Vaginal Ring for HIV Prevention: Modeling health outcomes, drug resistance and cost‐effectiveness

This paper evaluates the potential epidemiological impact and cost-effectiveness of dapivirine vaginal ring PrEP among 22- to 45-year-old women in KwaZulu-Natal, South Africa.

Financing & Costing, Research

Kenya Dapivirine Ring Rollout Scenarios

As Kenya considers introduction of the dapivirine ring, a new HIV prevention method for women, an outstanding question is how and where the ring should be introduced relative to oral PrEP. To support decision making, the PROMISE Consortium developed this analysis to consider several possible scenarios, defined by HIV incidence among women and adolescent girls…

Research, Service Delivery

Understanding Service Providers’ Knowledge of Oral PrEP and Attitudes Toward Provisionto Populations at Substantial HIV Risk in South Africa

This poster describes the results of a cross-sectional qualitative study, interviewing providers at public, private, and nongovernmental health facilities in South Africa offering PrEP to explore providers’ attitudes toward and experiences delivering PrEP to AGYW.

Research, Service Delivery

Creating demand for the Dapivirine vaginal ring

This presentation outlines lessons learned from ring clinical trials and oral PrEP programs in Kenya, South Africa, Uganda, and Zimbabwe that can be applied to the development of demand creation strategies.

Demand Creation/Marketing

Dapivirine Ring Design Guide: Human-Centered Design Research to Increase Uptake and Use

USAID's Center for Accelerating Innovation and Impact applied a human-centered design approach to better understand how IPM's dapivirine ring and other HIV prevention products could fit into young women's lives. This guide offers design concepts and tools to encourage and increase dapivirine ring uptake and use.

Demand Creation/Marketing

Microbicide Trials Network-043 – B-PROTECTED Study

Microbicide Trials Network-043, or B-PROTECTED, is a Phase IIIb open-label study that evaluated the safety and acceptability of the monthly dapivirine ring and daily oral PrEP in women who are breastfeeding, a time of heightened vulnerability for acquiring HIV.

Research

Use of the Dapivirine vaginal ring and effect on cervical cytology abnormalities

This study aims to determine if the dapivirine vaginal ring and the ring device alone (flexible silicone matrix polymer) was associated with the development of cervical cytology abnormalities.

Research, Service Delivery

Results from the HPTN 084 Trial

The HIV Prevention Trials Network (HPTN) hosted a community webinar to discuss the primary results of HPTN 084, a randomized, double-blind controlled trial designed to evaluate the efficacy and safety of long-acting injectable cabotegravir (CAB LA) to prevent the sexual acquisition of HIV in cisgender women in sub-Saharan Africa.

Research

Knowledge, Attitudes and Practices of PrEP Providers Working with Adolescent Girls and Young Women

A review of completed, ongoing and planned studies exploring Knowledge, Attitudes and Practices of PrEP Providers Working with Adolescent Girls and Young Women

Research

Vaginal Ring Acceptability and Related Preferences among Women in Low- and Middle-income Countries: A systematic review and narrative synthesis

The vaginal ring (VR) is a female-initiated drug-delivery platform used for different indications, including HIV pre-exposure prophylaxis (PrEP). This article outlines a systematic review of VR acceptability, values and preferences among women in low- and middle-income countries (LMIC) to inform further investment and/or guidance on VR use for HIV prevention.

Research