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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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19 October 2023

Measuring Effects of Counseling to Increase Pre-Exposure Prophylaxis Adherence and Partner Support in South Africa Using the Healthy Relationship Assessment Tool

This article from Global Health: Science and Practice describes the results of a study to investigate the impact of the Healthy Relationships Tool, part of the CHARISMA Toolkit, on PrEP adherence amongst women in Johannesburg, South Africa.

Research

External Link
12 October 2023

PrEP Ring Value Chain Situation Analysis – South Africa – 2021

This value chain situation analysis can support the introduction of the dapivirine ring in South Africa across two dimensions: considering and prioritizing delivery channels for the ring, and identifying critical steps for ring introduction, including opportunities to build on the introduction and scale-up of oral PrEP.

Normative Guidance/Policies, Service Delivery

Document
9 October 2023

Efficacy, Safety, Tolerability, and Pharmacokinetics of Long-acting Injectable Cabotegravir for HIV Pre-exposure Prophylaxis in Transgender Women: A secondary analysis of the HPTN 083 trial

This article from the Lancet HIV discusses the results of a secondary analysis of data from the HPTN 083 trial of cabotegravir for PrEP, looking specifically at the cohort of transgender women included in the study.

Research

External Link
29 August 2023

Changes in Relationships, HIV Risk, and Feelings towards PrEP: Findings from a qualitative explanatory study among participants in the CHARISMA intervention trial

This article from BMC Women’s Health explores women’s experiences with the CHARISMA randomized controlled trial, which tested whether the CHARISMA intervention mitigated relationship-based challenges to PrEP use, such as intimate partner violence, and looks into why the trial showed null results. Click here for more information on CHARISMA.

Research, Service Delivery

External Link
21 August 2023

Development of a Relationship Counselling Website to Identify and Mitigate Risk of Intimate Partner Violence in the Context of Women’s PrEP Use

This article from PLOS Digital Health discusses the results of beta-testing CHARISMA mobile, a digital resource to support lay counsellors help women access PrEP safely and and effectively by addressing dynamics of their relationships with male partners, including exposure to intimate partner violence. Click here for more information on CHARISMA.

Research, Service Delivery

External Link
21 August 2023

Dual Prevention Pill: Market Preparation and Introduction Strategy

This strategy, updated in August 2023, is intended for donors, governments, implementing partners and civil society to inform priorities and planning for DPP rollout. The strategy describes activities required to build a cohesive body of evidence and recommends an approach to DPP introduction to focus efforts. Where possible, activities will be embedded into existing programs…

Demand Creation/Marketing, Financing & Costing, Normative Guidance/Policies, Research, Supply Chain Management

Document
10 August 2023

Adolescent Girls and Young Women’s Experiences with Disclosing Oral PrEP or Dapivirine Vaginal Ring Use: A multi-country qualitative analysis

This article from AIDS and Behavior explores adolescent girls and young women’s experiences in disclosing use of oral PrEP and the dapivirine vaginal ring in South Africa, Uganda, and Zimbabwe.

Service Delivery

External Link
10 July 2023

Baseline Preferences for Oral Pre-Exposure Prophylaxis (PrEP) or Dapivirine Intravaginal Ring for HIV Prevention Among Adolescent Girls and Young Women in South Africa, Uganda and Zimbabwe (MTN-034/IPM-045 Study)

This journal article from PLOS ONE explored baseline preferences for oral PrEP or the dapivirine ring for AGYW (adolescent girls and young women) in South Africa, Uganda, and Zimbabwe.

Monitoring & Evaluation

External Link
13 March 2023

PrEP Use and HIV Seroconversion Rates in Adolescent Girls and Young Women from Kenya and South Africa: The POWER demonstration project

This article from the Journal of the International AIDS Society describes the POWER project, a prospective implementation science evaluation of PrEP delivery for adolescent girls and young women in family planning clinics in Kisumu, Kenya and youth and primary healthcare clinics in Cape Town and Johannesburg, South Africa.

Research, Service Delivery

External Link
6 March 2023

What Motivated Men to Start PrEP? A cross-section of men starting PrEP in Buffalo City Municipality, South Africa

This article from BMC Public Health discusses the results of qualitative interviews with cisgender, heterosexual men initiating PrEP in Buffalo City Municipality, South Africa to explore their perceived HIV acquisition risk, prevention needs, and preferences for PrEP initiation.

Demand Creation/Marketing, Research

External Link