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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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18 June 2024

Uganda Strategic Direction Summary, 2023

Uganda continues to accelerate reductions in new HIV infections and AIDS-related deaths, despite chronic infectious disease outbreaks, health system stressors, and economic fragility. This is reflected in Uganda’s HIV clinical cascade, which demonstrates substantial progress in finding, diagnosing, and successfully treating people living with HIV (PLHIV) since 2016. Today, an estimated 92% of Ugandans living…

Normative Guidance/Policies

Document
7 June 2024

Self-reported Removal and Expulsion of the Dapivirine Vaginal Ring: Qualitative reports from female ring users and their male partners in the Ring Study (IPM 027)

This article from BMC Public Health explores participants’ and their male partners’ discussions on accidental/purposeful vaginal ring removals during The Ring Study (IPM-027 clinical trial of the one month dapvirine vaginal ring).

Research

External Link
23 May 2024

Epidemiologically Informed HIV Pre-exposure Prophylaxis Targets for Uganda Using PrEP-it and the UNAIDS Population Size Estimate Tool

This poster, presented at the INTEREST 2024 conference in Cotonou, Benin, describes how the government of Uganda utilised the Sub-national HIV Estimates in Priority Populations (SHIPP) tool to set national PrEP targets.

Research

Document
26 March 2024

Discussing Early Results from the SEARCH Dynamic Choice Study

Watch the recording. Join AVAC and Professor Moses Kamya of Makerere University to find out why the early results of the SEARCH Dynamic Choice study were some of the most exciting to come out of CROI in 2024. Conducted in Kenya and Uganda, the study offered oral PrEP, PEP or injectable cabotegravir to both men…

Research

Event
4 March 2024

HIV Preexposure Prophylaxis With Emtricitabine and Tenofovir Disoproxil Fumarate Among Cisgender Women

This article from the Journal of the American Medical Association describes the results of a pooled analysis to measure HIV incidence among cisgender women with different adherence trajectories to oral PrEP with TDF/FTC.

Research

External Link
6 February 2024

Global Mapping of PrEP Ring Implementation Research and Programmatic Pilots

This analysis provides an overview of the 13 introduction studies that include the PrEP ring as one of the PrEP products under investigation alongside oral PrEP and/or CAB for PrEP as of November 2023. All of the PrEP ring studies are conducted in Sub-Saharan Africa and focus primarily on adolescent girls and young women (AGYW)…

Research

Document
22 January 2024

A Community-based Dynamic Choice Model for HIV Prevention Improves PrEP and PEP Coverage in Rural Uganda and Kenya: A cluster randomized trial

This article from Journal of the International AIDS Society describes the effect of a dynamic choice model for HIV prevention, delivered by community health workers with clinician support, on the use of biomedical prevention (including PrEP and PEP) amongst persons at risk of HIV in rural Kenya and Uganda. This research was undertaken as part…

Research, Service Delivery

External Link
13 December 2023

Value Chain Situation Analyses

Situation analyses are an initial step in supporting national planning for the introduction and scale-up of PrEP methods. These tools can be used by policymakers or others supporting policy development for new PrEP methods (e.g., nongovernmental organizations, donors) to conduct an analysis to assess the existing situation for the introduction of the new product. Value…

Normative Guidance/Policies, Research

15 November 2023

Quality Improvement Brief

The Quality Improvement Collaborative (QIC) is a component of the CATALYST study that refines and makes context-specific improvements to the enhanced service delivery package to make it scalable for delivering PrEP choice. The QIC’s multi-country design enables rich learning and problem-solving by providing QI faculty, advisors, coaches, and teams from all CATALYST countries opportunities to…

Monitoring & Evaluation

Document
6 November 2023

Adherence, Safety, and Choice of the Monthly Dapivirine Vaginal Ring or Oral Emtricitabine Plus Tenofovir Disoproxil Fumarate for HIV Pre-exposure Prophylaxis among African Adolescent Girls and Young Women: A randomised, open-label, crossover trial

This article from the Lancet HIV assesses product adherence, safety, and choice of oral PrEP compared with the dapivirine ring among adolescent girls and young women in South Africa, Uganda, and Zimbabwe.

Research

External Link