PEP needs some pep! Addressing PEP Neglect in HIV Prevention Research, Programming and Uptake

Thursday3November

PEP, post-exposure-prophylaxis, is an HIV prevention intervention marked by both great promise and profound neglect. It is useful in both occupational and non-occupational contexts – yet uptake, especially in non-occupational contexts – is poor in most places on the planet. Our panel will unpack the issues and offer research, policy, and programming ideas to address PEP neglect and realize its potential.

Speakers

Dr. James Ayieko, Kenya Medical Research Institute (KEMRI)
Dr. Julie Fox, Guy’s and St Thomas’ NHS Trust/ Kings College
Dr. Ken Mayer, Fenway Institute/Harvard
Njambi Njuguna, FHI 360/MOSAIC
Ace Robinson, PCAF

This webinar is presented by The Choice Agenda, a global forum for advocacy on the latest in HIV prevention research.

Featured Resources

External Link

Dynamic Choice HIV Prevention with Cabotegravir Long-acting Injectable in Rural Uganda and Kenya: A randomised trial extension

This article from The Lancet HIV discusses the results of the SEARCH dynamic choice study conducted in Kenya and Uganda, comparing outcomes between one group offered a choice between oral PrEP, post-exposure prophylaxis, and cabotegravir for PrEP, and a second group receiving the standard of care.

External Link

Role of HIV Self-testing in Strengthening HIV Prevention Services

This article from The Lancet HIV examines the potential role of HIV self-testing (HIVST) in achieving HIV prevention goals by looking at trials of use of HIVST with prevention tools such as pre-exposure prophylaxis (PrEP), post-exposure prophylaxis (PEP), and voluntary medical male circumcision (VMMC).

External Link

Client Experiences with “Dynamic Choice Prevention,” a Model for Flexible Patient-centred HIV Prevention Delivery in Rural Eastern Africa

This article from Journal of the International AIDS Society discusses client experiences of a dynamic choice model for HIV prevention piloted in Kenya and Uganda under the SEARCH study, where clients were supported to select HIV prevention method, testing mode, and service delivery channel from a range of options.

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Online Pharmacy PrEP and PEP: Technical considerations and learnings from Kenya

This document, developed by PATH, is intended as a how-to implementation guide for providing oral pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) via online pharmacy service delivery (ePrEP/ePEP) based on learnings and evidence from the ePrEP Kenya pilot study that ran from October 2022 through July 2024. The guide was developed to support ministries of…

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WHO Guidelines for HIV Post-exposure Prophylaxis

These guidelines developed by the World Health Organisation outline the latest recommendations and evidence on use of post-exposure prophylaxis (PEP).

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PEP FactSheet

This tool developed by the South Africa National Department of Health is intended to support clinical education efforts related to HIV PEP.

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PEP Counseling Job Aid

This tool developed by the South Africa National Department of Health is intended to support health care providers in counseling their clients about PEP.

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Clinical Algorithm for Initiation of HIV Post Exposure Prophylaxis (PEP) for HIV Prevention

This tool developed by the South Africa National Department of Health is intended to support health care providers in screening for PEP.

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Canada Guidelines on HIV PrEP & Nonoccupational PEP, 2017

The Canadian Guidelines on HIV PrEP and Nonoccupational PEP outline combination and on-demand prevention strategies to mitigate the risk of HIV acquisition.

Presentation

HIV Post-Exposure Prophylaxis (PEP) Training

This resource, produced by the South Africa National Department of Health, is a comprehensive training on post-exposure prophylaxis (PEP) provision for health care providers. Additional Resources: Clinical Algorithm for Initiation of HIV Post Exposure Prophylaxis (PEP) for HIV Prevention PEP Counseling Job Aid PEP FactSheet