New Data, New Opportunities: The expanding evidence base for the PrEP ring

Wednesday29November

Virtual

Three MTN studies – REACH, DELIVER, and B-PROTECTED – recently published critical new data on PrEP ring use among adolescent girls and young women (AGYW), pregnant individuals, and breastfeeding individuals in Africa. All studies offer compelling evidence that the ring is safe for use among these populations. Moreover, the REACH study is the first to examine what happens when AGYW are offered a choice of PrEP products – the ring or oral PrEP – to meet their needs and preferences. In this webinar, we’ll learn more about the results of these three studies and what they mean for national PrEP policies and programs in Africa.

Moderators

Kristine Torjesen, FHI 360
Nhlamulo Chantel Manganye, Wits Reproductive Health and HIV Institute

Presenters

Carolyne A. Akello, FHI 360
Katie Bunge, University of Pittsburgh Medical Center
Lisa Noguchi, Jhpiego
Michelle Rodolph, World Health Organization

This webinar is part of the Global PrEP Learning Network webinar series hosted by MOSAIC.

Featured Resources

Spreadsheet

Access Workbook for Cabotegravir for PrEP and Dapivirine Vaginal Ring

This workbook, compiled by the Global Fund, contains key access information relating to cabotegravir (CAB) for PrEP and the dapivirine vaginal ring (DVR) for all lower and middle income countries, including eligibility for Global Fund support, PEPFAR support status, regulatory status of CAB for PrEP and the DVR, access to non-profit product pricing, and information…

External Link

Self-reported Removal and Expulsion of the Dapivirine Vaginal Ring: Qualitative reports from female ring users and their male partners in the Ring Study (IPM 027)

This article from BMC Public Health explores participants’ and their male partners’ discussions on accidental/purposeful vaginal ring removals during The Ring Study (IPM-027 clinical trial of the one month dapvirine vaginal ring).

Document

MOSAIC (Maximizing Options to Advance Informed Choice for HIV Prevention)

Short introduction to MOSAIC, a project working across multiple countries to implement user-centered research and research translation efforts to identify, understand, and remove barriers to new product introduction, access, and use; coordinate and provide technical assistance to global, national, and subnational stakeholders to expedite product launch and scale-up; and strengthen the capacity of a wide…

Document

Access, Adherence, and Acute HIV Infections: A characterization of seroconversion with PrEP in Eswatini

This poster, presented at the INTEREST conference in Cotonou, Benin in 2024, outlines characteristics of seroconversions by women using oral PrEP or the dapivirine vaginal ring in Eswatini.

External Link

Lessons Learnt from Daily Oral PrEP Delivery to Inform National Planning for PrEP Ring Introduction for Women in Low-income and Middle-income Countries: A qualitative inquiry of international stakeholders

This article from BMJ Global Health synthesises lessons learnt from oral PrEP, based on discussions with international stakeholders, to inform the development of a costed rollout plan template for longer acting PrEP methods, including the dapivirine vaginal ring.

Document

Daily Oral PrEP, Event-Driven PrEP, PrEP Ring, and CAB PrEP Template Guidelines (Spanish)

The intent of this document is to provide adaptable guidelines to support the development and adoption of national guidelines that align with World Health Organization (WHO) pre-exposure prophylaxis (PrEP) recommendations and guidance, including those for tenofovir disoproxil fumarate (TDF)-based daily and event-driven oral PrEP, the monthly dapivirine vaginal ring (“PrEP ring” or “the ring”), and…

Document

PrEP Ring for Adolescent Girls and Youth Women: Summary of research findings

This brief outlines findings from a recent study which has published critical new data on use of the dapivirine vaginal ring (PrEP ring or ring) among adolescent girls and young women in eastern and southern Africa, offering evidence that the ring is safe, effective, and highly acceptable.

Presentation

PrEP Ring Safety Data in Adolescent Girls and Youth Women (AGYW)

This slide deck presents emerging evidence to support conversations on expanding pre-exposure prophylaxis (PrEP) ring access for adolescent girls and young women (AGYW) in policy and programmatic rollout.

Document

PrEP Ring for Pregnant and Breastfeeding Women: Summary of research findings in eastern and southern Africa

This brief outlines findings from recent studies which have published critical new data on use of the dapivirine vaginal ring (PrEP ring or ring) among pregnant and breastfeeding people in eastern and southern Africa, offering evidence that the PrEP ring is a safe and effective HIV prevention method for a broader population than was initially…

Presentation

PrEP Ring Safety Data in Pregnant and Breastfeeding Women

This slide deck presents emerging evidence to support conversations on expanding pre-exposure prophylaxis (PrEP) ring access for pregnant and breastfeeding women (PBFW) in policy and programmatic rollout.