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Over the last 20 years, the United States (US) government through the President’s Emergency Plan for AIDS Relief (PEPFAR) has worked collaboratively with the Government of Nigeria (GoN) to accelerate access to comprehensive, patient-centered HIV prevention, care, and treatment services. Today, over 1.9 million Nigerians living with HIV are accessing life-saving antiretroviral therapy (ART), indicating that Nigeria is making progress towards controlling the global HIV/AIDS pandemic. Nigeria has made incredible progress towards the UNAIDS 95-95-95 Fast-track targets (defined as 95 percent of people with HIV know their HIV status, 95 percent of those with diagnosed HIV infection are accessing ART, and 95 percent of those receiving ART have achieved an undetectable viral load); however, large numbers of new infections continue to be identified.