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The Cameroon Country Operational Plan 2023 (COP23) encompasses Fiscal Years (FY) 2024 and 2025. Under this plan, the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) team in Cameroon will implement innovative and targeted strategies to close HIV service gaps among vulnerable and key populations while continuing to work with the Government of the Republic of Cameroon (GRC), including the Ministry of Health (MOH) and the National AIDS Control Committee (NACC), donors, implementing partners (IPs) and civil society to support a sustainable, country-led response.