The Biomedical Prevention Implementation Collaborative (BioPIC)
A collaborative approach to HIV prevention product introduction
The Biomedical Prevention Implementation Collaborative (BioPIC) is documenting, analysing, and leveraging lessons learnt from PrEP programmes to accelerate the introduction of new PrEP products, including cabotegravir for PrEP. BioPIC achieves this through a range of activities, including serving as an essential clearinghouse to monitor the activities related to HIV prevention product introduction; a trusted convener of a wide-range of stakeholders; an important catalyst for investments in product introduction; and a custodian of the collaborative approach in product introduction. This work includes hosting the secretariat of the Coalition to Accelerate Access to Long-Acting PrEP.
Resources
- Shaping and Coordinating the Implementation Science Agenda for Injectable Cabotegravir for PrEP: The role of the Biomedical Prevention Implementation Collaborative (BioPIC)
- Adaptable Product Introduction Framework
- Integrated Study Tracker
- Injectable Cabotegravir Evidence Gap Tracker
- Long-acting PrEP Status Update
Think Tanks and Webinars
An ongoing series of think tanks and webinars, conducted by BioPIC, are generating key insights for people-centered product delivery.
True Choice in HIV Prevention Involves More than Product Options: Novel strategies in service delivery
November 2024
This webinar featured speakers from South Africa, Kenya, and Brazil discussing innovative PrEP delivery strategies to increase choice and uptake.
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Where’s the Equity? Including People with Disabilities in HIV Prevention Programming and Research
August 2024
This webinar explored the who, what, where, and how involved in acknowledging the importance of including people with disabilities in HIV prevention implementation and research.
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You Get What You Measure: Why Monitoring for PrEP Choice Helps Tell Our Story
July 2024
This webinar covered the current state of PrEP M&E and efforts to improve and simplify the data we collect, allowing our data to better reflect how people are using PrEP, support PrEP choice amongst the growing array of PrEP methods, and enhance the stories we can tell about PrEP program implementation.
Learn more.
Coordinating Implementation Science: PrEP and the Role of HIV Self-testing
June 2024
At this Think Tank, PrEP implementers and technical experts discussed and reviewed opportunities and challenges in the scale-up of HIV self-testing for PrEP initiation and continuation.
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Coordinating Implementation Science for CAB for PrEP: HIV Testing
June 2024
This Think Tank provided an opportunity for CAB for PrEP implementers to discuss and review emerging issues around HIV testing.
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PrEP and the Role of HIV Self-testing
May 2024
A panel of experts, including representatives from WHO, shared technical guidance on and experiences with rolling out HIVST for PrEP.
Learn more, and watch the webinar here.
Discussing Early Results from the SEARCH Dynamic Choice Study
April 2024
During this webinar, Professor Moses Kamya of Makerere University shared early insights from the SEARCH Dynamic Choice Study in Kenya and Uganda, which gave participants a choice between oral PrEP, PEP, and CAB for PrEP.
Learn more, and watch the webinar here.
Coordinating Implementation Science for CAB for PrEP: Linking Modellers with the Latest Implementation Science Evidence
March 2024
At this meeting, modellers of CAB for PrEP and implementation science study leads shared the latest data and insights from their respective studies.
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Coordinating Implementation Science: Taking Stock of PrEP Evidence
March 2024
This Think Tank provided an opportunity to both review existing PrEP evidence and identify priority evidence gaps to be explored and addressed further in future Think Tanks.
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Coordinating Implementation Science for CAB for PrEP: Early Insights from EBONI and PILLAR
February 2024
ViiV Healthcare, the manufacturer of CAB for PrEP, shared early insights from their two CAB for PrEP implementation studies, the EBONI and PILLAR studies.
Learn more.
Coordinating Implementation Science for CAB for PrEP: Linking Modellers with the Latest Implementation Science Evidence
September 2023
At this meeting, modellers of CAB for PrEP and implementation science study leads aligned on data and evidence needs to fill CAB for PrEP evidence gaps.
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Coordinating Implementation Science for CAB for PrEP: Inclusion of Key Populations
September 2023
This meeting, part of the BioPIC implementation science series, focused on strategies to include trans and gender diverse people, gay and bisexual men who have sex with men, sex workers, and people who use and inject drugs in implementation science projects as well as the rollout and scale-up of CAB for PrEP.
Learn more.
Coordinating Implementation Science for CAB for PrEP: Bridging from the HPTN 083 and 084 Open Label Extensions to Implementation
March 2023
This fourth meeting of the BioPIC implementation science series focused on lessons learnt from the HPTN 083 and 084 Open Label Extensions.
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Shaping and Strengthening Markets for a New Era of Choice-based HIV/SRH Programming: Lessons from HIV & FP product introduction
March 2023
As new HIV prevention products move closer to entering the market, there is an opportunity to design choice-based programs that apply lessons and successes from HIV and FP product introduction and push the envelope with new innovations. Yet delivery of biomedical HIV prevention options within FP settings remains nascent, despite a sharp rise in uptake of oral PrEP globally. Under BioPIC, AVAC and WHO convened a Think Tank with donors, implementing partners and advocates to discuss how to effectively grow and strengthen choice-based prevention markets in order to meet the diverse and comprehensive health needs of various populations.
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Coordinating Implementation Science for CAB for PrEP: Focus on Research and Surveillance during Pregnancy and Breastfeeding
November 2022
This third meeting of the BioPIC implementation science series focused on CAB for PrEP implementation research and surveillance during pregnancy and breastfeeding.
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Coordinating Implementation Science for CAB for PrEP: Focus on Delivery Models
June 2022
This second meeting of the BioPIC implementation science series focused on how CAB for PrEP can be integrated into existing community, pharmacy and facility-based delivery for HIV prevention.
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Generating Demand for HIV Biomedical Prevention in the Era of Choice
June 2022
In light of the emerging need to (re-)define how to generate demand for choice in HIV biomedical prevention, AVAC, under BioPIC, convened program implementers; social and behavioural change communication, marketing, and design thinking experts; behavioral economists; researchers; donors; and civil society to identify proven and promising strategies and models to more effectively reach and engage different populations. Nine experts/organizations drawn from both the HIV and family planning sectors shared insights from their previous and current demand generation interventions for different populations and geographical contexts.
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Coordinating Implementation Science for CAB for PrEP
April 2022
As implementation studies for injectable CAB for PrEP are being considered and as programs shift towards choice-based models for HIV prevention, there is a chance to correct for missed opportunities with oral PrEP rollout, understand client preferences and patterns of use, and ensure more effective coordination across geographies, populations, and projects. To facilitate this coordination, AVAC and WHO convened implementers, donors, members of civil society organisations, and the developer of CAB for PrEP to share plans for implementation studies.
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Modelling the Impact of Injectable CAB for PrEP on Drug Resistance
April 2022
An important consideration in the scale-up of injectable CAB for PrEP is the potential for development of Integrase Strand Transfer Inhibitor (INSTI) resistance. To help stakeholders understand this issue further, Professor Andrew Phillips from University College London shared the results of an exercise modelling the impact of the introduction of CAB for PrEP on INSTI resistance and AIDS-related mortality, as well as cost-effectiveness.
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HIV Testing and Injectable CAB for PrEP Introduction: What are the implications for HIV prevention scale-up and the HIV response?
December 2021
One challenge which has emerged with the introduction of CAB for PrEP is the risk of INSTI resistance amongst people who acquire HIV while taking CAB as prescribed. To address emerging evidence around testing algorithms and INSTI resistance in CAB users, AVAC and WHO convened a think tank with program implementers, testing experts, mathematical modelers, policy makers, donors, and civil society.
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Product Introduction/Implementation Project Planning for Next-Generation PrEP
September 2021
Early data from clinical trials has indicated that CAB for PrEP is safe and effective. With an accelerated timeline for introduction of CAB for PrEP, AVAC and WHO convened a think tank to strategize about demonstration projects and other planning for product introduction.
Learn more.